Promethazine is an H1 receptor blocking agent. Along with its antihistaminic action, it provides clinically useful sedative and antiemetic outcomes.
The commonest Unwanted effects are drowsiness, improvements in blood pressure, skin reactions, blood mobile improvements and breathing problems. Amplified excitability or irregular movements may well come about right after 1 dose of promethazine. If they do, talk to your health practitioner about utilizing A different medication.
Antihistamines and codeine are both of those contraindicated for use during the treatment of decreased respiratory tract signs or symptoms, including asthma.
Warning ought to be exercised when promethazine hydrochloride and codeine phosphate syrup is administered into a nursing woman.
Steer clear of using Promethazine HCl and Codeine Phosphate Oral Resolution in adolescents 12 to eighteen decades of age who have other possibility components that could enhance their sensitivity towards the respiratory depressant effects of codeine.
Nonetheless, this impact will not be steady and will be offset by an increased level of cervical dilation, which tends to shorten labor. Keep an eye on neonates subjected to opioids all through labor for indications of surplus sedation and respiratory despair.
This tends to happen Even though you choose Promethazine Hydrochloride and Codeine Phosphate Oral Solution accurately as prescribed by your healthcare company. Your chance of habit, abuse, and misuse is improved in the event you or possibly a member of the family includes a heritage of drug or Alcoholic beverages abuse or habit, or psychological health issues.
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People really should be suggested to measure Promethazine with Codeine Oral Option by having an precise measuring unit. A residence teaspoon isn't an accurate measuring system and could lead on to overdosage, particularly when a fifty percent a teaspoon is measured.
It's not necessarily recognized whether Promethazine HCl is excreted in human milk. For the reason that many medicine are excreted in human milk and because of the probable for significant adverse reactions in nursing infants from Promethazine HCl Oral Remedy, a choice ought to be manufactured no matter if to discontinue nursing or to discontinue the drug, taking into consideration the necessity of the drug to the mother.
Serious breathing complications. Promethazine HCl Oral Answer should not be Utilized in people with inadequate lung operate for example Persistent obstructive lung disease or respiratory challenges although sleeping (slumber apnea.)
Neuroleptic malignant syndrome (NMS) which may lead to Dying. Show you healthcare provider without delay if you have any of the following signs or symptoms of NMS:
Promethazine HCl Oral Resolution really should be utilised during pregnancy only if the prospective gain justifies the potential danger on the fetus.
Promethazine HCl Oral Answer needs to be employed cautiously in individuals with heart problems or with impairment of liver functionality.